ESP Biography

Why do some diseases affect only a handful of people worldwide? How do doctors diagnose conditions they’ve never seen before? And what happens when a cure doesn’t yet exist? In this interdisciplinary course, students will explore the world of rare diseases—conditions that affect fewer than 200,000 people in the United States, yet collectively impact over 30 million Americans. Through case studies, guest speakers, short documentary clips, and hands-on activities, students will learn about the biology behind rare diseases, the diagnostic challenges patients face, and the ethical and social dimensions of rare disease research. Topics may include (time permitting): The genetics of rare diseases Diagnostic odysseys and the role of medical detectives The role of the NIH’s Undiagnosed Diseases Program Patient perspectives and advocacy Drug development and clinical trials for small populations The global impact of rare diseases and health equity